Surface Plasmon Resonance biosensor analysis as a useful tool in FBDD

Advances in surface plasmon resonance biosensor analysis.

The number and diversity of surface plasmon resonance (SPR) biosensor applications continue to increase. Evolutions in instrument and sensor chip technology, experimental methodology, and data analysis are making it possible to examine a wider variety of biomolecular interactions in greater mechanistic detail. SPR biosensors are poised to make a significant impact in basic research and pharmace...

Surface plasmon resonance biosensor

[Biosensor based on surface plasmon resonance].

Sensitivity analysis of a nanowire-based surface plasmon resonance biosensor in the presence of surface roughness.

We have investigated the effect of surface roughness on the sensitivity of conventional and nanowire-based surface plasmon resonance (SPR) biosensors. The theoretical research was conducted using rigorous coupled-wave analysis with Gaussian surface profiles of gold films determined by atomic force microscopy. The results suggest that, when surface roughness ranges near 1 nm, the sensitivity of ...

A Low-cost Autosampler for Surface Plasmon Resonance Biosensor Platforms

− A low-cost autosampler for surface plasmon resonance (SPR) biosensor platforms has been designed and applied for the determination of the mutual diffusion coefficient of ethanol in water. Its configuration is simple and based on a motorized carousel-type set-up. The sample loading process comprises a Z-drive, along with a syringe type analyte extractor. Furthermore, a commercial peristaltic p...